TY - JOUR
T1 - Real-time three-dimensional color doppler echocardiography for characterizing the spatial velocity distribution and quantifying the peak flow rate in the left ventricular outflow tract
AU - Tsujino, Hiroyuki
AU - Jones, Michael
AU - Shiota, Takahiro
AU - Qin, Jian Xin
AU - Greenberg, Neil L.
AU - Cardon, Lisa A.
AU - Morehead, Annitta J.
AU - Zetts, Arthur D.
AU - Travaglini, Agnese
AU - Bauer, Fabrice
AU - Panza, Julio A.
AU - Thomas, James D.
N1 - Funding Information:
The authors acknowledge the assistance of the veterinary professional and technical staff of the Laboratory of Animal Medicine and Surgery, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD. This study was supported in part by Grant NCC9-60, National Aeronautics and Space Administration, Houston, TX.
PY - 2001
Y1 - 2001
N2 - Quantification of flow with pulsed-wave Doppler assumes a 'flat' velocity profile in the left ventricular outflow tract (LVOT), which observation refutes. Recent development of real-time, three-dimensional (3-D) color Doppler allows one to obtain an entire cross-sectional velocity distribution of the LVOT, which is not possible using conventional 2-D echo. In an animal experiment, the cross-sectional color Doppler images of the LVOT at peak systole were derived and digitally transferred to a computer to visualize and quantify spatial velocity distributions and peak flow rates. Markedly skewed profiles, with higher velocities toward the septum, were consistently observed. Reference peak flow rates by electromagnetic flow meter correlated well with 3-D peak flow rates (r = 0.94), but with an anticipated underestimation. Real-time 3-D color Doppler echocardiography was capable of determining cross-sectional velocity distributions and peak flow rates, demonstrating the utility of this new method for better understanding and quantifying blood flow phenomena. (E-mail: [email protected])
AB - Quantification of flow with pulsed-wave Doppler assumes a 'flat' velocity profile in the left ventricular outflow tract (LVOT), which observation refutes. Recent development of real-time, three-dimensional (3-D) color Doppler allows one to obtain an entire cross-sectional velocity distribution of the LVOT, which is not possible using conventional 2-D echo. In an animal experiment, the cross-sectional color Doppler images of the LVOT at peak systole were derived and digitally transferred to a computer to visualize and quantify spatial velocity distributions and peak flow rates. Markedly skewed profiles, with higher velocities toward the septum, were consistently observed. Reference peak flow rates by electromagnetic flow meter correlated well with 3-D peak flow rates (r = 0.94), but with an anticipated underestimation. Real-time 3-D color Doppler echocardiography was capable of determining cross-sectional velocity distributions and peak flow rates, demonstrating the utility of this new method for better understanding and quantifying blood flow phenomena. (E-mail: [email protected])
KW - 3-D echocardiography
KW - Color Doppler
KW - Doppler ultrasound
KW - Hemodynamics
UR - http://www.scopus.com/inward/record.url?scp=0035060320&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035060320&partnerID=8YFLogxK
U2 - 10.1016/S0301-5629(00)00270-2
DO - 10.1016/S0301-5629(00)00270-2
M3 - Article
C2 - 11295272
AN - SCOPUS:0035060320
SN - 0301-5629
VL - 27
SP - 69
EP - 74
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 1
ER -