Reassessment of the assumed A V oxygen content difference in the shunt calculation

R. A. Harrison, R. Davison, B. A. Shapiro, S. N. Meyers

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


A study was undertaken in 15 patients to compare measured and assumed arteriovenous oxygen (A V O2) content, differences and their effects on resultant shunt calculations. All patients were on volume ventilators and demonstrated a stable cardiovascular state. Simultaneous measurements of the O2 content of a pulmonary artery (PA) and of a superior vena cava (SVC) sample were compared. A mean A V O2 content difference of 3.5±0.8 volumes percent was obtained from the PA and 2.6±1.1 volumes percent from the SVC. The resultant shunt calculations derived from measured A V O2 content differences were compared with the calculation based on an assumed A V O2 content difference of 5 volumes percent. A method for extapolating a 'true' A V O2 content difference from an SVC blood sample was obtained. The extrapolated value resulted in a more representative 'true shunt' calculation in 13 of the 15 patients.

Original languageEnglish (US)
Pages (from-to)198-202
Number of pages5
JournalAnesthesia and analgesia
Issue number2
StatePublished - 1975

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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