Recent advances in gene therapy for atrial fibrillation

Shin Yoo*, Gail Elizabeth Geist, Anna Pfenniger, Markus Rottmann, Rishi Arora

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Atrial fibrillation (AF) is the most common heart rhythm disorder in adults and a major cause of stroke. Unfortunately, current treatments for AF are suboptimal as they are not targeting the molecular mechanisms underlying AF. In this regard, gene therapy is emerging as a promising approach for mechanism-based treatment of AF. In this review, we summarize recent advances and challenges in gene therapy for this important cardiovascular disease.

Original languageEnglish (US)
Pages (from-to)2854-2864
Number of pages11
JournalJournal of cardiovascular electrophysiology
Volume32
Issue number10
DOIs
StatePublished - Oct 2021

Keywords

  • atrial fibrillation
  • gene therapy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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