TY - JOUR
T1 - Recent progress in pediatric soft tissue sarcoma therapy
AU - Lautz, Timothy B.
AU - Hayes-Jordan, Andrea
PY - 2019/12
Y1 - 2019/12
N2 - Soft tissue sarcomas of childhood are a heterogenous group of tumors with a wide spectrum of presentations and outcomes. Most patients require multimodal therapy with chemotherapy, surgery and/or radiation. Improved outcomes in recent decades have been achieved through improvements in the comprehensive care of these children through large cooperative group studies, even as little progress has been made in the standard chemotherapy backbone. A thorough understanding of the nuances of surgical therapy for these children is required to minimize both the risk of local failure and the possibility of loss of vital form or function.
AB - Soft tissue sarcomas of childhood are a heterogenous group of tumors with a wide spectrum of presentations and outcomes. Most patients require multimodal therapy with chemotherapy, surgery and/or radiation. Improved outcomes in recent decades have been achieved through improvements in the comprehensive care of these children through large cooperative group studies, even as little progress has been made in the standard chemotherapy backbone. A thorough understanding of the nuances of surgical therapy for these children is required to minimize both the risk of local failure and the possibility of loss of vital form or function.
UR - http://www.scopus.com/inward/record.url?scp=85076006293&partnerID=8YFLogxK
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U2 - 10.1016/j.sempedsurg.2019.150862
DO - 10.1016/j.sempedsurg.2019.150862
M3 - Article
C2 - 31931970
AN - SCOPUS:85076006293
VL - 28
JO - Seminars in Pediatric Surgery
JF - Seminars in Pediatric Surgery
SN - 1055-8586
IS - 6
M1 - 150862
ER -