Recognition between V- and dumbbell-shaped molecules

Wing Yan Wong, Siu Fung Lee, Hoi Shan Chan, Thomas C.W. Mak, Chi Hin Wong, Lau Shan Huang, J. Fraser Stoddart*, Ken Cham Fai Leung

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A series of 2,6-bis(imino)pyridyl-based V-shaped compounds bearing various para-substituents on the terminal aromatic rings [C5H 3N(CHN-C6H4R)2; R = OMe, iPr, Me, H, Cl, F, and CF3] have been prepared and investigated for their reversible binding with the dumbbell-shaped cations NH2+-{CH2-C6H3(OMe-3,5) 2}2 and 9-anthryl-CH2-NH2 +-CH2-C6H3(OMe-3,5)2. Three crystalline V-shaped compounds and a dumbbell hexafluorophosphate were characterised in the solid state by X-ray structural analysis. The binding mode of the 1 : 1 V-shaped molecule·dumbbell complexes was evaluated by 1H NMR spectroscopy. The binding constants (90-400 M-1 in dichloromethane) and stoichiometries of the complexes were determined using the Method of Continuous Variations and the Rose-Drago Method based on 1H NMR spectroscopic data. In a series of V-shaped compounds, the binding strength with both dumbbell cations diminishes with the decreasing electron-donating ability of the R substituents. Specifically, one of the diimine V-shaped compounds shows a stronger binding with the symmetrical dumbbell than with the unsymmetrical anthracene-containing dumbbell. Fluorescence measurements of equimolar mixtures of the V-shaped compounds and the unsymmetrical dumbbell have revealed a reduced anthracene emission which is approximately 50% that of the original intensity. Rapid and complete dissociation (<5 min) of the V-shaped compounds from the dumbbells was realised using an excess of acid or base, whereas only partial dissociation of the complexes was achieved with a large excess of water (<1 h).

Original languageEnglish (US)
Pages (from-to)26382-26390
Number of pages9
JournalRSC Advances
Volume3
Issue number48
DOIs
StatePublished - Dec 28 2013

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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    Wong, W. Y., Lee, S. F., Chan, H. S., Mak, T. C. W., Wong, C. H., Huang, L. S., Stoddart, J. F., & Leung, K. C. F. (2013). Recognition between V- and dumbbell-shaped molecules. RSC Advances, 3(48), 26382-26390. https://doi.org/10.1039/c3ra43470b