Recognition-induced control and acceleration of a pyrrole Diels-Alder reaction

Raphaël Bennes, Marcos Sapró Babiloni, Wayne Hayes*, Douglas Philp

*Corresponding author for this work

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

The formation of two hydrogen bonds between an amidopyridine and a carboxylic acid controls the stereochemical outcome and significantly accelerates the rate of the Diels-Alder cycloaddition between a benzoylpyrrole and a maleimide.

Original languageEnglish (US)
Pages (from-to)2377-2380
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number12
DOIs
StatePublished - Mar 18 2001

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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