Recombinant human factor VIIa in the management of amyloid-associated factor X deficiency

Lisa Boggio, David Green*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

Factor X deficiency is an important complication of amyloidosis. It is associated with severe bleeding that is difficult to control with plasma or prothrombin complex concentrates. Splenectomy ameliorates the factor X deficiency, but achieving satisfactory haemostasis for this operation is problematic. We report that a new clotting concentrate, recombinant factor VIIa, readily controls bleeding and makes splenectomy feasible.

Original languageEnglish (US)
Pages (from-to)1074-1075
Number of pages2
JournalBritish Journal of Haematology
Volume112
Issue number4
DOIs
StatePublished - 2001

Keywords

  • Amyloid
  • Factor X deficiency
  • Haemostasis
  • Recombinant factor VIIa
  • Splenectomy

ASJC Scopus subject areas

  • Hematology

Fingerprint

Dive into the research topics of 'Recombinant human factor VIIa in the management of amyloid-associated factor X deficiency'. Together they form a unique fingerprint.

Cite this