Recovery of xenotropic virus but not ecotropic virus during graft-versus-host reaction in mice

J. A. Levy*, S. K. Datta, R. S. Schwartz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Graft-versus-host reaction (GVHR) enhanced the expression of endogenous xenotropic C-type RNA viruses and not of ecotropic C-type viruses in the spleens of CAF-1 hybrid mice. This observation suggests a specific xenotropic virus response during the GVHR in mice and indicates that ecotropic viruses are not necessarily expressed during GVHR. The possible role of xenotropic viruses in the GVHR-induced malignancy is considered.

Original languageEnglish (US)
Pages (from-to)262-268
Number of pages7
JournalClinical Immunology and Immunopathology
Volume7
Issue number2
DOIs
StatePublished - Mar 1977

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pathology and Forensic Medicine
  • Immunology

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