Red cell antibodies and the new immunology

G. Ramsey*

*Corresponding author for this work

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

The rapid advances of the new immunology are beginning to be applied to the classic problems of immunohematology. Red cell alloimmunization is an important problem in transfusion and pregnancy, and several recent lines of evidence suggest links between red cell antibodies and autoimmunity. Pathogenic red cell autoantibodies are being studied for their fine specificity and structure. Modulation of red cell antibody responses may become feasible by using immunosuppression, anti-idiotypic antibodies, or interleukin blockage. Various clinical cofactors may affect the likelihood of immune hemolysis. Finally, new antibody technologies are being developed that may prove useful in blood banking.

Original languageEnglish (US)
Pages (from-to)90-95
Number of pages6
JournalLaboratory Medicine
Volume25
Issue number2
DOIs
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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