Red cell cation transport: Differences between black and white school children

Maurizio Trevisan, Richard Cooper*, David Ostrow, Christopher Sempos, Steven Sparks, Seraphim Nanas, William Miller, Jeremiah Stamler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Differences in red cell sodium content and sodium-lithium countertransport were studied in black and white children with a mean age of 12 years. For both boys and girls red cell sodium content was higher in blacks and countertransport lower (P < 0.05). For both ethnic groups red cell sodium was lower in girls than boys and a consistent positive relationship was noted between body mass index and countertransport. Despite the lower red cell Na-Li countertransport values in black compared'to white j children, ia significant positive correlation with systolic blood pressure was found independent of adiposity. In contrast, no correlation was evident between Na-Li countertransport and blood pressure in the white children. If red cell cation transport is confirmed as a marker for hypertension, study of racial differences may help explain the twofold higher prevalence of this disease among blacks.

Original languageEnglish (US)
Pages (from-to)245-249
Number of pages5
JournalJournal of hypertension
Issue number3
StatePublished - Oct 1983


  • Children
  • Countertransport
  • Ethnic background
  • Hypertension
  • Sodium

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine


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