Reduced diffusion lung capacity in patients with type 2 diabetes mellitus predicts hospitalization for pneumonia

Oana L. Klein*, Lewis J. Smith, Matthew Tipping, Jie Peng, Mark V. Williams

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Among 4164 patients, those with type 2 diabetes mellitus (DM) had lower lung diffusion capacity (DLCO) compared with those without DM (DLCO mean ± SE: 15.7 ± 0.3 vs. 17.0 ± 0.2. mL/min/mm. Hg, p< 0.01). Reduced DLCO predicted hospitalization for pneumonia independent of diabetes control, severity and co-morbidities (OR = 2.4, CI 1.08-5.31).

Original languageEnglish (US)
Pages (from-to)e12-e15
JournalDiabetes Research and Clinical Practice
Volume92
Issue number1
DOIs
StatePublished - Apr 2011

Keywords

  • Carbon monoxide diffusing capacity (DLCO)
  • DM control/hemoglobin A1c
  • DM severity/DM medication
  • Heart failure (HF)
  • Hospitalization
  • LUNG function
  • Microalbuminuria
  • Microangiopathy
  • Pneumonia
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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