Reducing cardiovascular disparities through community-engaged implementation research: A national heart, lung, and blood institute workshop report

George A. Mensah*, Richard S. Cooper, Anna Maria Siega-Riz, Lisa A. Cooper, Justin D. Smith, C. Hendricks Brown, John M. Westfall, Elizabeth O. Ofili, Leshawndra N. Price, Sonia Arteaga, Melissa C. Green Parker, Cheryl R. Nelson, Bradley J. Newsome, Nicole Redmond, Rebecca A. Roper, Bettina M. Beech, Jada L. Brooks, Debra Furr-Holden, Samson Y. Gebreab, Wayne H. GilesRegina Smith James, Tené T. Lewis, Ali H. Mokdad, Kari D. Moore, Joseph E. Ravenell, Al Richmond, Nancy E. Schoenberg, Mario Sims, Gopal K. Singh, Anne E. Sumner, Roberto P. Treviño, Karriem S. Watson, M. Larissa Avilés-Santa, Jared P. Reis, Charlotte A. Pratt, Michael M. Engelgau, David C. Goff, Eliseo J. Pérez-Stable

*Corresponding author for this work

Research output: Contribution to journalArticle

25 Scopus citations


Cardiovascular disparities remain pervasive in the United States. Unequal disease burden is evident among population groups based on sex, race, ethnicity, socioeconomic status, educational attainment, nativity, or geography. Despite the significant declines in cardiovascular disease mortality rates in all demographic groups during the last 50 years, large disparities remain by sex, race, ethnicity, and geography. Recent data from modeling studies, linked micromap plots, and small-Area analyses also demonstrate prominent variation in cardiovascular disease mortality rates across states and counties, with an especially high disease burden in the southeastern United States and Appalachia. Despite these continued disparities, few large-scale intervention studies have been conducted in these high-burden populations to examine the feasibility of reducing or eliminating cardiovascular disparities. To address this challenge, on June 22 and 23, 2017, the National Heart, Lung, and Blood Institute convened experts from a broad range of biomedical, behavioral, environmental, implementation, and social science backgrounds to summarize the current state of knowledge of cardiovascular disease disparities and propose intervention strategies aligned with the National Heart, Lung, and Blood Institute mission. This report presents the themes, challenges, opportunities, available resources, and recommended actions discussed at the workshop.

Original languageEnglish (US)
Pages (from-to)213-230
Number of pages18
JournalCirculation research
Issue number2
StatePublished - Jan 2018



  • Cardiovascular diseases
  • Community-based participatory research
  • Geography
  • Social class
  • Social determinants of health

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Mensah, G. A., Cooper, R. S., Siega-Riz, A. M., Cooper, L. A., Smith, J. D., Hendricks Brown, C., Westfall, J. M., Ofili, E. O., Price, L. N., Arteaga, S., Green Parker, M. C., Nelson, C. R., Newsome, B. J., Redmond, N., Roper, R. A., Beech, B. M., Brooks, J. L., Furr-Holden, D., Gebreab, S. Y., ... Pérez-Stable, E. J. (2018). Reducing cardiovascular disparities through community-engaged implementation research: A national heart, lung, and blood institute workshop report. Circulation research, 122(2), 213-230.