Reducing time-to-treatment in underserved Latinas with breast cancer: The Six Cities Study

Amelie Ramirez*, Eliseo Perez-Stable, Frank Penedo, Gregory Talavera, J. Emilio Carrillo, María Fernández, Alan Holden, Edgar Munoz, Sandra San Miguel, Kipling Gallion

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


BACKGROUND The interaction of clinical and patient-level challenges following a breast cancer diagnosis can be a significant source of health care disparities. Failure to address specific cultural features that create or exacerbate barriers can lead to less-than optimal navigation results, specifically in Hispanic/Latino women. METHODS To address these disparities, the study leaders in San Antonio, Texas, and 5 other regional partners of the federally-funded Redes En Acción: The National Latino Cancer Research Network developed a culturally-tailored patient navigation intervention model for Latinas with breast cancer. RESULTS Compared with control patients, a higher percentage of navigated subjects initiated treatment within 30 days (69.0% versus 46.3%, P =.029) and 60 days (97.6% versus 73.1%, P =.001) following their cancer diagnosis. Time from cancer diagnosis to first treatment was lower in the navigated group (mean, 22.22 days; median, 23.00 days) than controls (mean, 48.30 days; median, 33.00 days). These results were independent of cancer stage at diagnosis and numerous characteristics of cancer clinics and individual participants. CONCLUSIONS Successful application of patient navigation increased the percentage of Latinas initiating breast cancer treatment within 30 and 60 days of diagnosis. This was achieved through navigator provision of services such as accompaniment to appointments, transportation arrangements, patient telephone support, patient-family telephone support, Spanish-English language translation, and assistance with insurance paperwork.

Original languageEnglish (US)
Pages (from-to)752-760
Number of pages9
Issue number5
StatePublished - Mar 1 2014


  • Latinas
  • breast cancer
  • culture
  • patient navigation
  • time-to-treatment

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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