Reference ranges of PR duration and P-wave indices in individuals free of cardiovascular disease: The Multi-Ethnic Study of Atherosclerosis (MESA)

Elsayed Z. Soliman*, Alvaro Alonso, Jeffrey R. Misialek, Aditya Jain, Karol E. Watson, Donald M. Lloyd-Jones, Joao Lima, Steven Shea, Gregory L. Burke, Susan R. Heckbert

*Corresponding author for this work

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

In this brief report, we provide normal reference ranges for PR duration [unadjusted and heart rate adjusted] and P-wave indices [duration, amplitude and terminal force in V1] in individuals free of cardiovascular disease and its risk factors. We used automatically processed digital ECG data from 1252 US participants [mean age 59 (± 10) years, 738 women, 588 whites, 207 African-Americans, 217 Hispanics, 240 Chinese] from the Multi-Ethnic Study of Atherosclerosis [MESA]. In multivariable adjusted linear regression models with PR and each P-wave variable as a separate outcome, significant age, sex and race differences in these markers were observed. Subsequently, we report reference ranges for abnormal [2nd and 98th percentiles], borderline abnormal [5th and 95th percentiles] and mean [SD] values of PR and P-wave indices stratified by age [middle age (45-64 years) and seniors (65-84 years)], sex [men and women] and race [whites, African Americans, Hispanics and Chinese].

Original languageEnglish (US)
Pages (from-to)702-706
Number of pages5
JournalJournal of Electrocardiology
Volume46
Issue number6
DOIs
StatePublished - Nov 2013

Keywords

  • MESA
  • P-wave indices
  • PR interval

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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