Refractory status epilepticus

Thomas P Bleck*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations


Purpose of review: Although conventional anticonvulsant agents can terminate status epilepticus in most cases, a substantial minority of patients develops medically refractory status and requires more aggressive care. This review explores the options available. Recent findings: Increasing numbers of previously unexpected etiologies for refractory status epilepticus continue to be reported. There are also some promising new therapies on the horizon, both for the short and the longer terms. Summary: Refractory status epilepticus, while a challenge to the intensivist, can be treated with drugs that are commonly used by intensivists. The cooperation of an interested electroencephalographer is vital.

Original languageEnglish (US)
Pages (from-to)117-120
Number of pages4
JournalCurrent opinion in critical care
Issue number2
StatePublished - Apr 1 2005


  • Ketamine
  • Lorazepam
  • Midazolam
  • Pentobarbital
  • Propofol
  • Refractory status epilepticus

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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