Abstract
In this research we develop generalized linear regression models for the mean of a quality-of-life-adjusted restricted survival time. Parameter and standard error estimates could be obtained from generalized estimating equations applied to pseudo-observations. Simulation studies with moderate sample sizes are conducted and an example from the International Breast Cancer Study Group Ludwig Trial V is used to illustrate the newly developed methodology.
Original language | English (US) |
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Pages (from-to) | 398-404 |
Number of pages | 7 |
Journal | Biometrics |
Volume | 63 |
Issue number | 2 |
DOIs | |
State | Published - Jun 2007 |
Keywords
- Gap time
- Inverse weighting
- Nonparametric
- Quality-of-life
- Successive events
ASJC Scopus subject areas
- General Agricultural and Biological Sciences
- Applied Mathematics
- General Biochemistry, Genetics and Molecular Biology
- General Immunology and Microbiology
- Statistics and Probability