Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation

John E.A. Blair; Sanford M. Zeigler; Jayesh Mehta; Seema Singhal; William Cotts

doi:10.1016/j.healun.2008.11.918

Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation

John E.A. Blair, Sanford M. Zeigler, Jayesh Mehta, Seema Singhal, William Cotts^*

^*Corresponding author for this work

Medicine, Hematology Oncology Division

Research output: Contribution to journal › Article

4 Scopus citations

Abstract

Primary cardiac amyloid has a dismal prognosis and most treatments are experimental with highly variable results. Although autologous stem-cell transplant in conjunction with high-dose chemotherapy has yielded regression of amyloid in other body tissues, the presence of cardiac involvement contraindicates stem-cell transfer due to high treatment mortality. We describe the successful treatment of cardiac amyloid using autologous stem-cell transplantation and the resultant regression of the cardiac amyloid.

Original language	English (US)
Pages (from-to)	746-748
Number of pages	3
Journal	Journal of Heart and Lung Transplantation
Volume	28
Issue number	7
DOIs	https://doi.org/10.1016/j.healun.2008.11.918
State	Published - Jul 1 2009

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine
Transplantation

Access to Document

10.1016/j.healun.2008.11.918

Fingerprint Dive into the research topics of 'Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation'. Together they form a unique fingerprint.

Cite this

Blair, J. E. A., Zeigler, S. M., Mehta, J., Singhal, S., & Cotts, W. (2009). Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation. Journal of Heart and Lung Transplantation, 28(7), 746-748. https://doi.org/10.1016/j.healun.2008.11.918

@article{102337b31c3c4612bdec2d9677a5a3ae,

title = "Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation",

abstract = "Primary cardiac amyloid has a dismal prognosis and most treatments are experimental with highly variable results. Although autologous stem-cell transplant in conjunction with high-dose chemotherapy has yielded regression of amyloid in other body tissues, the presence of cardiac involvement contraindicates stem-cell transfer due to high treatment mortality. We describe the successful treatment of cardiac amyloid using autologous stem-cell transplantation and the resultant regression of the cardiac amyloid.",

author = "Blair, {John E.A.} and Zeigler, {Sanford M.} and Jayesh Mehta and Seema Singhal and William Cotts",

year = "2009",

month = jul,

day = "1",

doi = "10.1016/j.healun.2008.11.918",

language = "English (US)",

volume = "28",

pages = "746--748",

journal = "Journal of Heart and Lung Transplantation",

issn = "1053-2498",

publisher = "Elsevier USA",

number = "7",

}

TY - JOUR

T1 - Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation

AU - Blair, John E.A.

AU - Zeigler, Sanford M.

AU - Mehta, Jayesh

AU - Singhal, Seema

AU - Cotts, William

PY - 2009/7/1

Y1 - 2009/7/1

N2 - Primary cardiac amyloid has a dismal prognosis and most treatments are experimental with highly variable results. Although autologous stem-cell transplant in conjunction with high-dose chemotherapy has yielded regression of amyloid in other body tissues, the presence of cardiac involvement contraindicates stem-cell transfer due to high treatment mortality. We describe the successful treatment of cardiac amyloid using autologous stem-cell transplantation and the resultant regression of the cardiac amyloid.

AB - Primary cardiac amyloid has a dismal prognosis and most treatments are experimental with highly variable results. Although autologous stem-cell transplant in conjunction with high-dose chemotherapy has yielded regression of amyloid in other body tissues, the presence of cardiac involvement contraindicates stem-cell transfer due to high treatment mortality. We describe the successful treatment of cardiac amyloid using autologous stem-cell transplantation and the resultant regression of the cardiac amyloid.

UR - http://www.scopus.com/inward/record.url?scp=67649085910&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67649085910&partnerID=8YFLogxK

U2 - 10.1016/j.healun.2008.11.918

DO - 10.1016/j.healun.2008.11.918

M3 - Article

C2 - 19560707

AN - SCOPUS:67649085910

VL - 28

SP - 746

EP - 748

JO - Journal of Heart and Lung Transplantation

JF - Journal of Heart and Lung Transplantation

SN - 1053-2498

IS - 7

ER -