Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation

John E.A. Blair; Sanford M. Zeigler; Jayesh Mehta; Seema Singhal; William Cotts

doi:10.1016/j.healun.2008.11.918

Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation

John E.A. Blair, Sanford M. Zeigler, Jayesh Mehta, Seema Singhal, William Cotts^*

^*Corresponding author for this work

Medicine, Hematology Oncology Division

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Primary cardiac amyloid has a dismal prognosis and most treatments are experimental with highly variable results. Although autologous stem-cell transplant in conjunction with high-dose chemotherapy has yielded regression of amyloid in other body tissues, the presence of cardiac involvement contraindicates stem-cell transfer due to high treatment mortality. We describe the successful treatment of cardiac amyloid using autologous stem-cell transplantation and the resultant regression of the cardiac amyloid.

Original language	English (US)
Pages (from-to)	746-748
Number of pages	3
Journal	Journal of Heart and Lung Transplantation
Volume	28
Issue number	7
DOIs	https://doi.org/10.1016/j.healun.2008.11.918
State	Published - Jul 1 2009

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine
Transplantation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.healun.2008.11.918

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abstract = "Primary cardiac amyloid has a dismal prognosis and most treatments are experimental with highly variable results. Although autologous stem-cell transplant in conjunction with high-dose chemotherapy has yielded regression of amyloid in other body tissues, the presence of cardiac involvement contraindicates stem-cell transfer due to high treatment mortality. We describe the successful treatment of cardiac amyloid using autologous stem-cell transplantation and the resultant regression of the cardiac amyloid.",

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AU - Mehta, Jayesh

AU - Singhal, Seema

AU - Cotts, William

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AB - Primary cardiac amyloid has a dismal prognosis and most treatments are experimental with highly variable results. Although autologous stem-cell transplant in conjunction with high-dose chemotherapy has yielded regression of amyloid in other body tissues, the presence of cardiac involvement contraindicates stem-cell transfer due to high treatment mortality. We describe the successful treatment of cardiac amyloid using autologous stem-cell transplantation and the resultant regression of the cardiac amyloid.

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Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation

Abstract

ASJC Scopus subject areas

UN SDGs

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