Regression of Cardiac Amyloid After Autologous Stem-cell Transplantation

John E.A. Blair, Sanford M. Zeigler, Jayesh Mehta, Seema Singhal, William Cotts*

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Primary cardiac amyloid has a dismal prognosis and most treatments are experimental with highly variable results. Although autologous stem-cell transplant in conjunction with high-dose chemotherapy has yielded regression of amyloid in other body tissues, the presence of cardiac involvement contraindicates stem-cell transfer due to high treatment mortality. We describe the successful treatment of cardiac amyloid using autologous stem-cell transplantation and the resultant regression of the cardiac amyloid.

Original languageEnglish (US)
Pages (from-to)746-748
Number of pages3
JournalJournal of Heart and Lung Transplantation
Volume28
Issue number7
DOIs
StatePublished - Jul 1 2009

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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