Regression of rat primary mammary tumors following dietary d-limonene

J. A. Elegbede; C. E. Elson; M. A. Tanner; A. Qureshi; M. N. Gould

Regression of rat primary mammary tumors following dietary d-limonene

J. A. Elegbede, C. E. Elson, M. A. Tanner, A. Qureshi, M. N. Gould

Statistics and Data Science

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Abstract

The effects of d-limonene on rat mammary tumors were investigated. Following the appearance of mammary tumors induced by 7,12-dimethylbenz[a]anthracene in female (W/Fu x F344)F₂ rats, animals were assigned to pairs in which 1 rat was fed a diet containing 10% d-limonene and the other was pair fed an isocaloric diet containing 10% cellulose. There was a highly significant increase in the regression of the first tumors in the rats fed d-limonene. In addition, d-limonene given at this time inhibited the formation of subsequent multiple tumors in these rats.

Original language	English (US)
Pages (from-to)	323-325
Number of pages	3
Journal	Journal of the National Cancer Institute
Volume	76
Issue number	2
State	Published - 1986

ASJC Scopus subject areas

Oncology
Cancer Research

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abstract = "The effects of d-limonene on rat mammary tumors were investigated. Following the appearance of mammary tumors induced by 7,12-dimethylbenz[a]anthracene in female (W/Fu x F344)F2 rats, animals were assigned to pairs in which 1 rat was fed a diet containing 10% d-limonene and the other was pair fed an isocaloric diet containing 10% cellulose. There was a highly significant increase in the regression of the first tumors in the rats fed d-limonene. In addition, d-limonene given at this time inhibited the formation of subsequent multiple tumors in these rats.",

author = "Elegbede, {J. A.} and Elson, {C. E.} and Tanner, {M. A.} and A. Qureshi and Gould, {M. N.}",

year = "1986",

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AU - Elegbede, J. A.

AU - Elson, C. E.

AU - Tanner, M. A.

AU - Qureshi, A.

AU - Gould, M. N.

PY - 1986

Y1 - 1986

N2 - The effects of d-limonene on rat mammary tumors were investigated. Following the appearance of mammary tumors induced by 7,12-dimethylbenz[a]anthracene in female (W/Fu x F344)F2 rats, animals were assigned to pairs in which 1 rat was fed a diet containing 10% d-limonene and the other was pair fed an isocaloric diet containing 10% cellulose. There was a highly significant increase in the regression of the first tumors in the rats fed d-limonene. In addition, d-limonene given at this time inhibited the formation of subsequent multiple tumors in these rats.

AB - The effects of d-limonene on rat mammary tumors were investigated. Following the appearance of mammary tumors induced by 7,12-dimethylbenz[a]anthracene in female (W/Fu x F344)F2 rats, animals were assigned to pairs in which 1 rat was fed a diet containing 10% d-limonene and the other was pair fed an isocaloric diet containing 10% cellulose. There was a highly significant increase in the regression of the first tumors in the rats fed d-limonene. In addition, d-limonene given at this time inhibited the formation of subsequent multiple tumors in these rats.

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Regression of rat primary mammary tumors following dietary d-limonene

Abstract

ASJC Scopus subject areas

UN SDGs

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