Starved thyroidectomized, ad-renalectomized, adrenal-demedullated and sham operated rats were exposed to 4° for 3 hr and their heart lipoprotein lipase activities compared to those of animals maintained at room temperature. The lipoprotein lipase activity in the hearts of the thyroidectomized rats was comparable to that of the sham operated animals when expressed as units/heart. The enzyme activities in the hearts of the adrenalectomized and adrenal-demedullated rats were about 50% lower than those of the controls. In all animals, exposure to cold temperature induced significant increases in the myo-cardial lipoprotein lipase activity. In normal rats this effect could not be reversed by the administration of insulin. It is concluded that the increases in lipoprotein lipase activity in the hearts of rats exposed to cold temperatures are not dependent on adrenal and thyroid hormones.
|Original language||English (US)|
|Number of pages||4|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Jul 1974|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)