Regulatory long non-coding RNAs and neuronal disorders

Jhumku D. Kohtz; Emily G. Berghoff

doi:10.1016/j.physbeh.2010.01.015

Regulatory long non-coding RNAs and neuronal disorders

Jhumku D. Kohtz^*, Emily G. Berghoff

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Increasing evidence suggests that GABA neuropathies play a major role in a variety of neuronal disorders. In addition, the role of non-coding RNAs in regulating a wide range of cellular processes is an intense area of investigation. This commentary discusses the intersection of these two fields, a corollary to the finding that adult hippocampal GABAergic interneuron development is controlled by an embryonic non-coding RNA during development.

Original language	English (US)
Pages (from-to)	250-254
Number of pages	5
Journal	Physiology and Behavior
Volume	100
Issue number	3
DOIs	https://doi.org/10.1016/j.physbeh.2010.01.015
State	Published - Jun 2010

Funding

This work was supported by the American Recovery and Reinvestment Act, NICHD RHD05650AZ to JDK.

Keywords

GABA
Non-coding RNA
Rett syndrome
Transcription

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Behavioral Neuroscience

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10.1016/j.physbeh.2010.01.015

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abstract = "Increasing evidence suggests that GABA neuropathies play a major role in a variety of neuronal disorders. In addition, the role of non-coding RNAs in regulating a wide range of cellular processes is an intense area of investigation. This commentary discusses the intersection of these two fields, a corollary to the finding that adult hippocampal GABAergic interneuron development is controlled by an embryonic non-coding RNA during development.",

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AU - Berghoff, Emily G.

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AB - Increasing evidence suggests that GABA neuropathies play a major role in a variety of neuronal disorders. In addition, the role of non-coding RNAs in regulating a wide range of cellular processes is an intense area of investigation. This commentary discusses the intersection of these two fields, a corollary to the finding that adult hippocampal GABAergic interneuron development is controlled by an embryonic non-coding RNA during development.

KW - GABA

KW - Non-coding RNA

KW - Rett syndrome

KW - Transcription

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Regulatory long non-coding RNAs and neuronal disorders

Abstract

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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