Relationship between physical activity and health-related utility among knee osteoarthritis patients

Larry M. Manheim*, Dorothy Dunlop, Jing Song, Pamela Semanik, Jungwha Lee, Rowland W. Chang

*Corresponding author for this work

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Objective. To estimate the relationship between physical activity and health-related utility for people with knee osteoarthritis (OA) and implications for designing cost-effective interventions. Methods. We used generalized estimating equation regression analysis to estimate partial association of accelerometermeasured physical activity levels with health-related utility after controlling for demographics, health status, knee OA severity level, pain, and functioning. Results. Moving from the lowest to the middle tertile of physical activity level was associated with a 0.071 (P < 0.01) increase in health-related utility after controlling for demographics and a 0.036 (P < 0.05) increase in utility after controlling for demographics, health status, knee OA severity level, weight, pain, and functional impairments. Conclusion. Intervention programs that move individuals out of the lowest tertile of physical activity have the potential to be cost effective.

Original languageEnglish (US)
Pages (from-to)1094-1098
Number of pages5
JournalArthritis Care and Research
Volume64
Issue number7
DOIs
StatePublished - Jul 2012

ASJC Scopus subject areas

  • Rheumatology

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