Relationship between white matter pathology and performance on the General Movement Assessment and the Test of Infant Motor Performance in very preterm infants

Colleen Peyton*, Edward Yang, Masha Kocherginsky, Lars Adde, Toril Fjørtoft, Ragnhild Støen, Arend F. Bos, Christa Einspieler, Michael D. Schreiber, Michael E. Msall

*Corresponding author for this work

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: Cerebral Magnetic Resonance Imaging, the General Movement Assessment, and the Test of Infant Motor Performance are all tools that can predict neurodevelopmental outcome in preterm infants. However, how these tests relate to each other is unclear. Aims: To examine the relationship between cerebral Magnetic Resonance Imaging measured at term age, and the General Movement Assessment and Test of Infant Motor Performance measured at 10-15 weeks post-term age. Study design: Prospectively collected data in a sample of very preterm infants. Subjects: Fifty-three infants (23 female, 30 male) with a median gestational age of 28 weeks (range: 23-30 weeks) and a median birth weight of 1000 g (range: 515-1465 g). Outcome measures: Test of Infant Motor Performance, General Movement Assessment. Results: Infants with abnormal white matter were significantly more likely to have both abnormal general movements (p = 0.01) and abnormal Test of Infant Motor Performance scores (p = 0.001). Infants with abnormal general movements were significantly more likely to have lower Test of Infant Motor Performance Scores (p = 0.01). Conclusions: Abnormal white matter is related to motor deviations as measured by the General Movement Assessment and the Test of Infant Motor Performance as early as 3 months post-term age in a cohort of preterm infants.

Original languageEnglish (US)
Pages (from-to)23-27
Number of pages5
JournalEarly Human Development
Volume95
DOIs
StatePublished - Apr 1 2016

Fingerprint

Premature Infants
Pathology
Dyskinesias
Magnetic Resonance Imaging
White Matter
Birth Weight
Gestational Age
Outcome Assessment (Health Care)

Keywords

  • General movements
  • MRI
  • Test of Infant Motor Performance

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Peyton, Colleen ; Yang, Edward ; Kocherginsky, Masha ; Adde, Lars ; Fjørtoft, Toril ; Støen, Ragnhild ; Bos, Arend F. ; Einspieler, Christa ; Schreiber, Michael D. ; Msall, Michael E. / Relationship between white matter pathology and performance on the General Movement Assessment and the Test of Infant Motor Performance in very preterm infants. In: Early Human Development. 2016 ; Vol. 95. pp. 23-27.
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Relationship between white matter pathology and performance on the General Movement Assessment and the Test of Infant Motor Performance in very preterm infants. / Peyton, Colleen; Yang, Edward; Kocherginsky, Masha; Adde, Lars; Fjørtoft, Toril; Støen, Ragnhild; Bos, Arend F.; Einspieler, Christa; Schreiber, Michael D.; Msall, Michael E.

In: Early Human Development, Vol. 95, 01.04.2016, p. 23-27.

Research output: Contribution to journalArticle

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AU - Adde, Lars

AU - Fjørtoft, Toril

AU - Støen, Ragnhild

AU - Bos, Arend F.

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