Relationship of family and personal history to the occurrence of depression in persons with alzheimer's disease

Z. A. Butt*, M. E. Strauss

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

The authors tested the associations of family history and personal history of depression with mood disorders among patients with Alzheimer's disease (AD; N = 161). Considered individually, a positive family history and a positive personal history each conferred increased risk for depression in AD. Conjointly, neither family nor personal history accounted for a substantial amount of the variance in syndromal depression after the onset of AD, Most depressed AD patients in this sample did not have a positive family history or a previous episode of depression. Our understanding of the etiology and course of depression and dementia may be augmented with further neuropsychological and brain-imaging studies of the neuropathological substrates shared by these illnesses.

Original languageEnglish (US)
Pages (from-to)249-254
Number of pages6
JournalAmerican Journal of Geriatric Psychiatry
Volume9
Issue number3
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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