Relationships of low density lipoprotein cholesterol with age and other factors: A cross-sectional analysis of the CARDIA study

D. R. Jacobs, G. L. Burke, K. Liu, G. Cutter, G. Hughes, S. Hulley, S. Sidney

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Presumed evolution of low density lipoprotein cholesterol (LDL-C) was studied in a baseline cross-sectional survey of 4955 18-30 year old men and women of various sociodemographic backgrounds. Specifically studied were the influences on LDL-C and the change of LDL-C with age of race, gender, education, diet, physical activity, fatness and fitness. Men increased about 20 mg/dl per 10 years of age, while women increased about 3 mg/dl. Increasing education was found to be associated with higher LDL-C in blacks, but with lower LDL-C in whites. Higher Keys diet score and body mass index were positively associated with LDL-C, while higher total caloric intake, vigorous physical activity, duration on a treadmill exercise test and usual intake of alcohol were negatively associated with LDL-C. The finding of a different relationship of LDL-C to increasing education in whites than in blacks suggests a cultural or behavioral influence in rate of increase in LDL-C.

Original languageEnglish (US)
Pages (from-to)32-38
Number of pages7
JournalAnnals of Clinical Research
Volume20
Issue number1-2
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Medicine(all)

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