Reliability of assessing change with sequential coronary angiography

Katherine M. Detre*, Sheryl F. Kelsey, Eugene R. Passamani, Marian R. Fisher, John F. Brensike, James W. Battaglini, John M. Richardson, Irving K. Loh, Neil J. Stone, Robert F. Aldrich, Robert I. Levy, Stephen E. Epstein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Data are presented from a study evaluating the reliability of sequential angiography in estimating changes in coronary lesions. Three panels of three expert anglographers each read on two separate, independent occasions 18 sets of paired angiograms taken 24 months apart. All readers were blinded to the temporal sequence of the films, clinical data, and ventriculography information. The need for simultaneous viewing and reading of the two films, for training sessions, and for allowance to be made for apparent differences arising from boundary definitions prior to final analysis was demonstrated. Under stringent conditions (determination of change based on agreement of at least two out of three panels of physicians) it was possible to ascertain change in coronary atherosclerosis from sequential sets of coronary angiograms with good reliability. However, single-panel readings ylelded an unacceptable overestimate of the number of patients with lesion changes.

Original languageEnglish (US)
Pages (from-to)816-823
Number of pages8
JournalAmerican heart journal
Issue number4 PART 1
StatePublished - Oct 1982

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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