Renal Doppler evaluation in the child with hypertension

A reasonable screening discriminator?

Sumit Chhadia, Richard A Cohn, Gulsah Vural, James S Donaldson*

*Corresponding author for this work

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background: Hypertension is diagnosed in 1-5% of children, and 5-10% of those hypertensive children have renovascular disease. The gold standard for a diagnosis of renal artery stenosis is arteriography, and Doppler ultrasound (Doppler US) continues to be advocated as a useful screening test. Objective: The purpose of this study was to determine the utility of Doppler US in children as a screening tool and to better define clinical features of children in whom arteriography should be performed. Materials and methods: This retrospective study evaluated the imaging and clinical parameters for all children who had a renal US with Doppler followed by a diagnostic arteriogram for the evaluation of hypertension during a 12-year period at a tertiary children's hospital. Sixty-two children were included. We evaluated each child's clinical parameters and placed each child into one of three categories of hypertension: mild, moderate or severe. Results: Eleven of 17 kidneys with proven renal artery stenosis were detected with Doppler US (sensitivity 64%). Six children with renal artery stenosis were missed by Doppler US, four of whom had segmental artery lesions. Of the children with positive renal artery stenosis on arteriography, all but three (79%) were classified as having moderate to severe hypertension. Conclusion: Doppler US is a useful screening examination when evaluating children with hypertension, detecting renal artery stenosis in most affected children. The clinical risk classifications are helpful in guiding which children should proceed with arteriography regardless of the Doppler US results.

Original languageEnglish (US)
Pages (from-to)1549-1556
Number of pages8
JournalPediatric Radiology
Volume43
Issue number12
DOIs
StatePublished - Dec 1 2013

Fingerprint

Hypertension
Kidney
Doppler Ultrasonography
Renal Artery Obstruction
Angiography
Tertiary Care Centers
Retrospective Studies
Arteries

Keywords

  • Angiography
  • Children
  • Doppler ultrasound
  • Renovascular hypertension

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Renal Doppler evaluation in the child with hypertension: A reasonable screening discriminator?",
abstract = "Background: Hypertension is diagnosed in 1-5{\%} of children, and 5-10{\%} of those hypertensive children have renovascular disease. The gold standard for a diagnosis of renal artery stenosis is arteriography, and Doppler ultrasound (Doppler US) continues to be advocated as a useful screening test. Objective: The purpose of this study was to determine the utility of Doppler US in children as a screening tool and to better define clinical features of children in whom arteriography should be performed. Materials and methods: This retrospective study evaluated the imaging and clinical parameters for all children who had a renal US with Doppler followed by a diagnostic arteriogram for the evaluation of hypertension during a 12-year period at a tertiary children's hospital. Sixty-two children were included. We evaluated each child's clinical parameters and placed each child into one of three categories of hypertension: mild, moderate or severe. Results: Eleven of 17 kidneys with proven renal artery stenosis were detected with Doppler US (sensitivity 64{\%}). Six children with renal artery stenosis were missed by Doppler US, four of whom had segmental artery lesions. Of the children with positive renal artery stenosis on arteriography, all but three (79{\%}) were classified as having moderate to severe hypertension. Conclusion: Doppler US is a useful screening examination when evaluating children with hypertension, detecting renal artery stenosis in most affected children. The clinical risk classifications are helpful in guiding which children should proceed with arteriography regardless of the Doppler US results.",
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Renal Doppler evaluation in the child with hypertension : A reasonable screening discriminator? / Chhadia, Sumit; Cohn, Richard A; Vural, Gulsah; Donaldson, James S.

In: Pediatric Radiology, Vol. 43, No. 12, 01.12.2013, p. 1549-1556.

Research output: Contribution to journalArticle

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