Reprint of: Healthy Weight and Obesity Prevention: JACC Health Promotion Series

Carl J. Lavie; Deepika Laddu; Ross Arena; Francisco B. Ortega; Martin A. Alpert; Robert F. Kushner

doi:10.1016/j.jacc.2018.10.024

Reprint of: Healthy Weight and Obesity Prevention: JACC Health Promotion Series

Carl J. Lavie^*, Deepika Laddu, Ross Arena, Francisco B. Ortega, Martin A. Alpert, Robert F. Kushner

^*Corresponding author for this work

Medicine, Endocrinology Division

Research output: Contribution to journal › Review article › peer-review

41 Scopus citations

Abstract

Overweight and obesity have reached epidemic levels in the United States and worldwide, and this has contributed to substantial cardiovascular and other health risks. However, controversy exists concerning the causes of obesity and effective modalities for its prevention and treatment. There is also controversy related to the concept of metabolically healthy obesity phenotype, the “obesity paradox,” and on the importance of fitness to protect individuals who are overweight or obese from cardiovascular diseases. In this state-of-the-art review, the authors focus on “healthy weight” with the emphasis on the pathophysiologic effects of weight gain on the cardiovascular system; mechanistic/triggering factors; and the role of preventive actions through personal, education/environment, and societal/authoritative factors, as well as factors to provide guidance for caregivers of health promotion. Additionally, the authors briefly review metabolically healthy obesity, the obesity paradox, and issues beyond lifestyle consideration for weight loss with medications and bariatric surgery.

Original language	English (US)
Pages (from-to)	3027-3052
Number of pages	26
Journal	Journal of the American College of Cardiology
Volume	72
Issue number	23
DOIs	https://doi.org/10.1016/j.jacc.2018.10.024
State	Published - Dec 11 2018

Funding

Dr. Ortega receives support for research activity from the Spanish Ministry of Economy and Competitiveness and FEDER (DEP2016-79512-R); additional funding from the University of Granada, Plan Propio de Investigación 2016, Excellence actions: Unit of Excellence on Exercise and Health (UCEES); and the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 667302. Dr. Kushner has served on the advisory board for Novo Nordisk, Weight Watchers, and Retrofit. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Keywords

cardiovascular disease
healthy weight
obesity

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jacc.2018.10.024

Cite this

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abstract = "Overweight and obesity have reached epidemic levels in the United States and worldwide, and this has contributed to substantial cardiovascular and other health risks. However, controversy exists concerning the causes of obesity and effective modalities for its prevention and treatment. There is also controversy related to the concept of metabolically healthy obesity phenotype, the “obesity paradox,” and on the importance of fitness to protect individuals who are overweight or obese from cardiovascular diseases. In this state-of-the-art review, the authors focus on “healthy weight” with the emphasis on the pathophysiologic effects of weight gain on the cardiovascular system; mechanistic/triggering factors; and the role of preventive actions through personal, education/environment, and societal/authoritative factors, as well as factors to provide guidance for caregivers of health promotion. Additionally, the authors briefly review metabolically healthy obesity, the obesity paradox, and issues beyond lifestyle consideration for weight loss with medications and bariatric surgery.",

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AB - Overweight and obesity have reached epidemic levels in the United States and worldwide, and this has contributed to substantial cardiovascular and other health risks. However, controversy exists concerning the causes of obesity and effective modalities for its prevention and treatment. There is also controversy related to the concept of metabolically healthy obesity phenotype, the “obesity paradox,” and on the importance of fitness to protect individuals who are overweight or obese from cardiovascular diseases. In this state-of-the-art review, the authors focus on “healthy weight” with the emphasis on the pathophysiologic effects of weight gain on the cardiovascular system; mechanistic/triggering factors; and the role of preventive actions through personal, education/environment, and societal/authoritative factors, as well as factors to provide guidance for caregivers of health promotion. Additionally, the authors briefly review metabolically healthy obesity, the obesity paradox, and issues beyond lifestyle consideration for weight loss with medications and bariatric surgery.

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Reprint of: Healthy Weight and Obesity Prevention: JACC Health Promotion Series

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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