Research using clinical registries in children's surgical care

Clinical registries provide a valuable opportunity to study specific diagnoses or conditions with a broader scope than possible using individual center-based series and with more clinical detail than typically available in administrative data sources. These registries amass structured data with uniform definitions, thus facilitating reliable adoption and consistent use across contributing sites. By compiling granular data from a multitude of geographically diverse sites, clinical registries allow investigation of rare outcomes, comparison of practice and cost variation, and benchmarking across institutions. Registries may track cohorts of patients over time, providing unique longitudinal follow-up that cannot be obtained from many alternate data sources. As clinical registries become more prevalent, research conducted using these registries is increasing and helping to expand knowledge boundaries in children's surgery. The purpose of this review is to provide an overview of several of the most common clinical registries used in children's surgery and explore the strengths and limits of these tools in the conduct of meaningful health services research.