Residue-specific pK(a) measurements of the β-peptide and mechanism of pH-induced amyloid formation

Keyphrases

• Helix 100%
• Amyloid Formation 100%
• PH-induced 100%
• Amino Acid Residues 40%
• Glutamic Acid 40%
• Amyloidosis 40%
• Random Coil 40%
• NMR Spectroscopy 20%
• Alzheimer's Disease 20%
• Extrinsic Factors 20%
• Solution Conditions 20%
• Electrostatic Interaction 20%
• Side Chain 20%
• Histidine Residue 20%
• Appropriate Model 20%
• Histidine 20%
• Ionizable Groups 20%
• Charged Groups 20%
• Charged Amino Acids 20%
• Peptide Fragments 20%
• Aspartic Acid 20%
• Sodium Dodecyl Sulfate 20%
• Acid Residue 20%
• Dissociation Constant 20%
• Sheet Structure 20%
• Tyrosine Amino Acids 20%
• Trifluoroethanol 20%
• Polar Amino Acids 20%
• Unfavorable Interaction 20%
• PKa Values 20%
• Macrodipole 20%
• Sulfate Solution 20%

Biochemistry, Genetics and Molecular Biology

• Solution and Solubility 100%
• Amyloid Protein 100%
• Conformation 66%
• Amino Acids 66%
• Amyloidosis 66%
• Glutamic Acid 66%
• Histidine 66%
• Static Electricity 33%
• Dissociation Constant 33%
• Tyrosine 33%
• Sodium Dodecyl Sulfate 33%
• Cyanocobalamin 33%
• Aspartic Acid 33%

Chemistry

• Dissociation Exponent 100%
• formation 100%
• Histidine 66%
• Amino Acid 66%
• Glutamic Acid 66%
• Electrostatic Interaction 33%
• Dissociation Constant 33%
• NMR Spectroscopy 33%
• Sodium Dodecyl Sulfate 33%
• Aspartic Acid 33%