Respiratory self-gating for free-breathing abdominal phase-contrast blood flow measurements

Ning Jin, Robert J. Lewandowski, Reed A. Omary, Andrew C. Larson

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Purpose: To demonstrate the feasibility of using a free- breathing (FB) respiratory self-gated (RSG) approach for abdominal phase-contrast (PC) blood flow measurements. Materials and Methods: PC-magnetic resonance imaging (MRI) flow measurements were performed within the right renal artery, common hepatic artery, and main portal vein during breath-hold (BH) and FB with both signal averaging and RSG in eight healthy volunteers. The resultant images were qualitatively scored by two independent reviewers blinded to acquisition techniques. Blood flow volume and cross-sectional vessel size measurements were compared for three techniques. Results: The overall efficiency for the RSG-PC sequence was 38.9% ± 4.7%. Images acquired with RSG effectively mitigated respiratory motion artifacts, which were clearly evident within FB signal-averaged images. RSG produced similar image quality to that of BH techniques (P > 0.146) and resulted in similar vessel size measurements (P = 0.694). Flow results for both FB RSG and signal-averaged reconstructions correlated well with BH flow measurements (r = 0.97 and 0.92, P < 0.001). However, only the RSG methods demonstrated excellent absolute agreement with BH-PC flow measurements (P = 0.600), with signal- averaged methods resulting in significant overestimations. Conclusion: RSG methods can limit respiratory motion artifacts to reduce flow measurement inaccuracies during free-breathing PC measurements in the abdomen

Original languageEnglish (US)
Pages (from-to)860-868
Number of pages9
JournalJournal of Magnetic Resonance Imaging
Volume29
Issue number4
DOIs
StatePublished - Apr 1 2009

Keywords

  • Abdomen
  • Flow
  • Phase contrast
  • Respiratory self-gating

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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