Resting and total energy expenditure in patients with inflammatory bowel disease

Robert F. Kushner*, Dale A. Schoeller

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

63 Scopus citations


Patients with inflammatory bowel disease often present with weight loss. Among possible causes, an elevated energy expenditure has frequently been suggested but is the least documented. In this study resting metabolic rate (RMR) and total daily energy expenditure (TDEE) were measured in 15 outpatients with inflammatory bowel diseases and in eight healthy control subjects. Measured RMR as a percentage of that predicted from fat-free mass was not significantly different for control subjects (102 ± 9.8%, x̄ ± SD) and patients (100 ± 13.3%). TDEE, expressed as a multiple of RMR, was 1.70 ± 0.31 for control subjects and 1.78 ± 0.24 for patients. When patients were subgrouped as ≥ 90% or < 90% desirable body weight, a mean increase over RMR predicted from fat-free mass was seen in the underweight patients (106 ± 9.3%) but not in normalweight patients (99.0 ± 15.6%). Mean TDEE/RMR values for the patient subgroups were 1.70 ± 0.30 and 1.88 ± 0.08, respectively. We conclude that stable outpatients with inflammatory bowel disease have only a minimal increase in energy needs.

Original languageEnglish (US)
Pages (from-to)161-165
Number of pages5
JournalAmerican Journal of Clinical Nutrition
Issue number1
StatePublished - Jan 1991


  • Energy expenditure
  • Inflammatory bowel disease
  • Resting metabolic rate

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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