Results from the survey for preservation of adolescent reproduction (SPARE) study: Gender disparity in delivery of fertility preservation message to adolescents with cancer

Tobias S. Köhler, Laxmi A. Kondapalli, Amul Shah, Sarah Chan, Teresa K. Woodruff, Robert E. Brannigan

Research output: Contribution to journalArticlepeer-review

124 Scopus citations

Abstract

Purpose: Diminished reproductive capacity is a devastating consequence of life-sparing therapies for childhood malignancy. In 2006, the American Society of Clinical Oncology (ASCO) published fertility preservation recommendations (ASCOR) emphasizing the importance of early discussion and intervention for fertility preservation strategies. Using the Survey for Preservation of Adolescent REproduction (SPARE), we sought to determine fertility preservation attitudes and practice patterns post-ASCOR from pediatric oncology specialists nationwide. Materials and methods: The SPARE survey consists of 22 questions assessing pediatric oncology specialists' attitudes and practice patterns toward fertility preservation. Broad perspectives on fertility preservation, including a willingness to discuss fertility, knowledge of current fertility preservation methods and awareness of ASCOR, were assessed. Results: The majority of respondents acknowledged that fertility threats are a major concern for them and agreed that all pubertal cancer patients should be offered a fertility consultation, but only 46% reported they refer male pubertal cancer patients to a fertility specialist prior to cancer treatment >50% of the time, and only 12% reported they refer female pubertal cancer patients to a fertility specialist prior to cancer treatment > 50% of the time. While 44% of respondents were familiar with the 2006 ASCOR, only 39% of those utilized them to guide decision-making in greater than half of their patients. Conclusion: Our study demonstrates pediatric oncologists' motivation to preserve fertility in pediatric cancer patients; however, barriers to both gamete cryopreservation and referral to fertility specialists persist. Female pubertal patients are referred to fertility preservation specialists with much less frequency than are male pubertal patients, highlighting a disparity.

Original languageEnglish (US)
Pages (from-to)269-277
Number of pages9
JournalJournal of Assisted Reproduction and Genetics
Volume28
Issue number3
DOIs
StatePublished - Mar 2011

Keywords

  • Cancer
  • Cryopreservation
  • Fertility preservation
  • Pediatric oncology
  • Survey

ASJC Scopus subject areas

  • Reproductive Medicine
  • Genetics
  • Obstetrics and Gynecology
  • Developmental Biology
  • Genetics(clinical)

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