Rethinking antioxidants in the intensive care unit

Manu Jain; Navdeep S. Chandel

doi:10.10.1164/rccm.201307-1380CP

Rethinking antioxidants in the intensive care unit

Manu Jain, Navdeep S. Chandel^*

^*Corresponding author for this work

Medicine, Pulmonary Division

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

Recently there was yet another clinical trial using antioxidants that failed in patients with critical illness. In this perspective, we suggest that antioxidants likely interfere with the normal immune response, thus contributing to the lack of efficacy in patients with critical illness.

Original language	English (US)
Pages (from-to)	1283-1285
Number of pages	3
Journal	American journal of respiratory and critical care medicine
Volume	188
Issue number	11
DOIs	https://doi.org/10.10.1164/rccm.201307-1380CP
State	Published - Dec 1 2013

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

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10.10.1164/rccm.201307-1380CP

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title = "Rethinking antioxidants in the intensive care unit",

abstract = "Recently there was yet another clinical trial using antioxidants that failed in patients with critical illness. In this perspective, we suggest that antioxidants likely interfere with the normal immune response, thus contributing to the lack of efficacy in patients with critical illness.",

author = "Manu Jain and Chandel, {Navdeep S.}",

year = "2013",

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doi = "10.10.1164/rccm.201307-1380CP",

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AU - Chandel, Navdeep S.

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AB - Recently there was yet another clinical trial using antioxidants that failed in patients with critical illness. In this perspective, we suggest that antioxidants likely interfere with the normal immune response, thus contributing to the lack of efficacy in patients with critical illness.

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Rethinking antioxidants in the intensive care unit

Abstract

ASJC Scopus subject areas

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