Return cycle mapping after entrainment of ventricular tachycardia

Takashi Nitta, Richard B. Schuessler*, Masataka Mitsuno, Chris K. Rokkas, Fumitaka Isobe, Christopher S. Cronin, James Lewis Cox, John P. Boineau

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Background - The central common pathway, which is the target for ablation in reentrant ventricular tachycardia can be localized by entrainment mapping techniques. However, localization of the pathway is not always possible because of the elevated pacing threshold and the low voltage and fractionated potentials at the pathway. We examined whether return cycle mapping after entrainment localizes the pathway without pacing at the pathway or recording the potentials from the pathway and determined the required electrode resolution to localize the pathway. Methods and Results - Epicardial mapping was performed with 253 unipolar electrodes during and after entrainment of 13 morphologies of ventricular tachycardia that were induced in dogs 4 days after infarction. The return cycle was calculated by subtracting the first activation time from the second activation time after the last stimulus and the return cycle distribution map was constructed for each stimulation site. The return cycle isochrones equal to the ventricular tachycardia cycle length converged on the lines of conduction block irrespective of the stimulation site, and the central common pathway was localized at the region between the intersections of the return cycle isochrones after entrainment from different stimulation sites. The potentials from the central common pathway were not required to localize the pathway, and the mapping accuracy did not change with or without analysis of the potentials from the pathway. According to the correlation between the electrode resolution and the mapping accuracy an interelectrode distance of 8.5 mm was estimated as sufficient resolution for successful tachycardia termination during radiofrequency ablation guided by return cycle mapping. Conclusions - Return cycle mapping after entrainment localizes the central common pathway without pacing at the pathway or recording the potentials from the pathway. This new mapping technique could improve the success rate of the ablative procedures.

Original languageEnglish (US)
Pages (from-to)1164-1175
Number of pages12
Issue number12
StatePublished - Mar 31 1998


  • Entrainment
  • Mapping
  • Reentry
  • Tachycardia
  • Ventricles

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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