Reversal of left ventricular dysfunction after renal transplantation

R. K. Burt, S. Gupta-Burt, W. N. Suki, C. G. Barcenas, J. J. Ferguson, C. T. Van Buren

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

We report the cases of four patients with end-stage renal disease and New York Heart Association class III or IV heart failure of nonischemic origin as documented by coronary angiography. Because of left ventricular dysfunction (left ventricular end-diastolic pressure, 23 to 30 mm Hg; ejection fraction, 20% to 35%), all four patients were initially considered poor surgical candidates for renal transplantation. These same four patients became asymptomatic, however, with markedly improved cardiac function (ejection fraction, 43% to 69%) detected as early as 6 and 14 days after renal engraftment. Therefore, there exists a subset of patients with end-stage renal disease in whom congestive heart failure should not be considered a contraindication to renal transplantation. We conclude that some dialysis dependent patients who manifest symptomatic heart failure of nonischemic origin have a reversible cardiomyopathy and should not be denied renal transplantation.

Original languageEnglish (US)
Pages (from-to)635-640
Number of pages6
JournalAnnals of internal medicine
Volume111
Issue number8
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Internal Medicine

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