Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: A case report

C. L. Epting, R. R. Wolfe, S. H. Abman, G. H. Deutsch, D. Ivy*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

We describe a 2-year-old child with severe pulmonary hypertension due to a patent ductus arteriosus (PDA) with plexiform lesions on lung biopsy. Despite high basal pulmonary vascular resistance with minimal responsiveness to inhaled nitric oxide and other vasodilators, and advanced plexogenic arteriopathy on lung biopsy, her pulmonary hypertension completely resolved after PDA ligation and during 8 years of follow-up.

Original languageEnglish (US)
Pages (from-to)182-185
Number of pages4
JournalPediatric cardiology
Volume23
Issue number2
DOIs
StatePublished - Mar 1 2002

Keywords

  • Atrial natriuretic peptide
  • Congenital heart disease
  • Nitric oxide
  • Patent ductus arteriosus
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

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