Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: A case report

C. L. Epting; R. R. Wolfe; S. H. Abman; G. H. Deutsch; D. Ivy

doi:10.1007/s00246-001-0044-9

Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: A case report

C. L. Epting, R. R. Wolfe, S. H. Abman, G. H. Deutsch, D. Ivy^*

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

We describe a 2-year-old child with severe pulmonary hypertension due to a patent ductus arteriosus (PDA) with plexiform lesions on lung biopsy. Despite high basal pulmonary vascular resistance with minimal responsiveness to inhaled nitric oxide and other vasodilators, and advanced plexogenic arteriopathy on lung biopsy, her pulmonary hypertension completely resolved after PDA ligation and during 8 years of follow-up.

Original language	English (US)
Pages (from-to)	182-185
Number of pages	4
Journal	Pediatric cardiology
Volume	23
Issue number	2
DOIs	https://doi.org/10.1007/s00246-001-0044-9
State	Published - Mar 1 2002

Keywords

Atrial natriuretic peptide
Congenital heart disease
Nitric oxide
Patent ductus arteriosus
Pulmonary hypertension

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Cardiology and Cardiovascular Medicine

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10.1007/s00246-001-0044-9

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title = "Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: A case report",

abstract = "We describe a 2-year-old child with severe pulmonary hypertension due to a patent ductus arteriosus (PDA) with plexiform lesions on lung biopsy. Despite high basal pulmonary vascular resistance with minimal responsiveness to inhaled nitric oxide and other vasodilators, and advanced plexogenic arteriopathy on lung biopsy, her pulmonary hypertension completely resolved after PDA ligation and during 8 years of follow-up.",

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AU - Deutsch, G. H.

AU - Ivy, D.

PY - 2002/3/1

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N2 - We describe a 2-year-old child with severe pulmonary hypertension due to a patent ductus arteriosus (PDA) with plexiform lesions on lung biopsy. Despite high basal pulmonary vascular resistance with minimal responsiveness to inhaled nitric oxide and other vasodilators, and advanced plexogenic arteriopathy on lung biopsy, her pulmonary hypertension completely resolved after PDA ligation and during 8 years of follow-up.

AB - We describe a 2-year-old child with severe pulmonary hypertension due to a patent ductus arteriosus (PDA) with plexiform lesions on lung biopsy. Despite high basal pulmonary vascular resistance with minimal responsiveness to inhaled nitric oxide and other vasodilators, and advanced plexogenic arteriopathy on lung biopsy, her pulmonary hypertension completely resolved after PDA ligation and during 8 years of follow-up.

KW - Atrial natriuretic peptide

KW - Congenital heart disease

KW - Nitric oxide

KW - Patent ductus arteriosus

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Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: A case report

Abstract

Keywords

ASJC Scopus subject areas

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