Reversal of the pattern of respiratory variation of Doppler inflow velocities in constrictive pericarditis during mechanical ventilation

Ibrahim A. Abdalla, R. Daniel Murray, Hamdy E. Awad, William J. Stewart, James D. Thomas, Allan L. Klein*

*Corresponding author for this work

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Background: Spontaneous inspiration causes a characteristic decrease of the mitral valve (MV) and puLrnonary venous (PV) flow velocities obtained by Doppler echocardiography in patients with constrictive pericarditis (CP). This has been explained by the decrement it causes in the intrathoracic pressure. Positive pressure ventilation (PPV) causes an increment of intratlloraclc pressure with meclmnical inspiration. Therefore the pattern of respiratory variatipn produced during PPV may differ from that seen during spontaneous breathing. Objective: Our goal was to desct4be the effect of PPV on the pattern and magnitude of respiratory variation of MV and PV flow velocities in CP. Methods: We performed intraoperative pulsed Doppler transesophageal echocardiography on 15 patients (13 men, mean age 52 ± 15 years) with CP after general anesthesia and before sternotomy and pericardial stripping. The peak velocity and tEmevelocity integral (TVI) of the mitrvJ inflow E and A waves and the PV systolic and diastolic waves were measured at onset of irmpication and expiration for 3 to 6 respiratory cycles. Respiratory phase was monitored with a heat-sensitive nasal thermistor. The percent change En Doppler flow velocities from mechanical inspiration' (INS) to mechanical expiration (EXP) was calculated with the formula %change = INS - EXP/INS x 100. Results. The peak velocity of the mitral inflow E wave was significantly higher during mechanical inspiration tllan 'expiration (57 ± 14.5 versus 47 ± 13.9 cm/s, P < .001). Tlxis represented a percent change of 18% ± 7.9% from expication to inspiration. The mean TVI of the mitral Enflow E was also higher during mechanical inspiration than expiration (P = .02). The peak velocity of the PV D wave was lztgher during mechanical inspiration than expiration (39 ± I7.8 versus 28 ± 14.7 cm/s, P < .001). This represented a mean percent change of 28% ± 13.8%. The εan value of the TVI for the PV D wave was also significantly greater during mechenical inspiration than expiration (P < .05). Conclusions: Positive pressure ventilation reverses the pattern of respiratory variation of the MV and PV flow velocities in CP. The percent change in the peak velocities of the MV and PV flows produced by PPV is the same range reported in CP during spontaneous breathing.

Original languageEnglish (US)
Pages (from-to)827-831
Number of pages5
JournalJournal of the American Society of Echocardiography
Volume13
Issue number9
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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