Reversible and chemically programmable micelle assembly with DNA block-copolymer amphiphiles

Zhi Li, Yi Zhang, Paige Fullhart, Chad A. Mirkin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

155 Scopus citations

Abstract

We report a general solid-phase synthesis strategy for a novel class of DNA block copolymer amphiphiles. The assembled spherical micelle structures exhibit recognition properties defined by their DNA sequences and can be used to build higher-ordered structures through hybridization with materials that possess complementary DNA. This work is an important step toward creating DNA modified structures that can act as phase transfer agents and carriers of nanovesicles.

Original languageEnglish (US)
Pages (from-to)1055-1058
Number of pages4
JournalNano letters
Volume4
Issue number6
DOIs
StatePublished - Jun 2004

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

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