Reversible and chemically programmable micelle assembly with DNA block-copolymer amphiphiles

Zhi Li; Yi Zhang; Paige Fullhart; Chad A. Mirkin

doi:10.1021/nl049628o

Reversible and chemically programmable micelle assembly with DNA block-copolymer amphiphiles

Zhi Li, Yi Zhang, Paige Fullhart, Chad A. Mirkin^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

183 Scopus citations

Abstract

We report a general solid-phase synthesis strategy for a novel class of DNA block copolymer amphiphiles. The assembled spherical micelle structures exhibit recognition properties defined by their DNA sequences and can be used to build higher-ordered structures through hybridization with materials that possess complementary DNA. This work is an important step toward creating DNA modified structures that can act as phase transfer agents and carriers of nanovesicles.

Original language	English (US)
Pages (from-to)	1055-1058
Number of pages	4
Journal	Nano letters
Volume	4
Issue number	6
DOIs	https://doi.org/10.1021/nl049628o
State	Published - Jun 2004

ASJC Scopus subject areas

Bioengineering
General Chemistry
General Materials Science
Condensed Matter Physics
Mechanical Engineering

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10.1021/nl049628o

Cite this

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title = "Reversible and chemically programmable micelle assembly with DNA block-copolymer amphiphiles",

abstract = "We report a general solid-phase synthesis strategy for a novel class of DNA block copolymer amphiphiles. The assembled spherical micelle structures exhibit recognition properties defined by their DNA sequences and can be used to build higher-ordered structures through hybridization with materials that possess complementary DNA. This work is an important step toward creating DNA modified structures that can act as phase transfer agents and carriers of nanovesicles.",

author = "Zhi Li and Yi Zhang and Paige Fullhart and Mirkin, {Chad A.}",

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AU - Zhang, Yi

AU - Fullhart, Paige

AU - Mirkin, Chad A.

PY - 2004/6

Y1 - 2004/6

N2 - We report a general solid-phase synthesis strategy for a novel class of DNA block copolymer amphiphiles. The assembled spherical micelle structures exhibit recognition properties defined by their DNA sequences and can be used to build higher-ordered structures through hybridization with materials that possess complementary DNA. This work is an important step toward creating DNA modified structures that can act as phase transfer agents and carriers of nanovesicles.

AB - We report a general solid-phase synthesis strategy for a novel class of DNA block copolymer amphiphiles. The assembled spherical micelle structures exhibit recognition properties defined by their DNA sequences and can be used to build higher-ordered structures through hybridization with materials that possess complementary DNA. This work is an important step toward creating DNA modified structures that can act as phase transfer agents and carriers of nanovesicles.

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DO - 10.1021/nl049628o

M3 - Article

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JO - Nano letters

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Reversible and chemically programmable micelle assembly with DNA block-copolymer amphiphiles

Abstract

ASJC Scopus subject areas

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