Review: 5-fluorouracil cardiotoxicity: A critical review

W. J. Gradishar; E. E. Vokes

doi:10.1093/oxfordjournals.annonc.a057793

Review: 5-fluorouracil cardiotoxicity: A critical review

W. J. Gradishar^*, E. E. Vokes

^*Corresponding author for this work

Medicine, Hematology Oncology Division

Research output: Contribution to journal › Review article › peer-review

98 Scopus citations

Abstract

5-Fluorouracil is a commonly administered chemotherapy agent that has infrequently been associated with cardiotoxicity. This review highlights the clinical features of this syndrome as described in reports from the medical literature. Clinical and laboratory evidence supporting proposed underlying mechanisms are reviewed.

Original language	English (US)
Pages (from-to)	409-414
Number of pages	6
Journal	Annals of Oncology
Volume	1
Issue number	6
DOIs	https://doi.org/10.1093/oxfordjournals.annonc.a057793
State	Published - Nov 1990

Keywords

5-Fluorouracil
Angina
Coronary spasm
Myocardial infarction
Thrombosis
Toxicity

ASJC Scopus subject areas

Hematology
Oncology

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10.1093/oxfordjournals.annonc.a057793

Cite this

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title = "Review: 5-fluorouracil cardiotoxicity: A critical review",

abstract = "5-Fluorouracil is a commonly administered chemotherapy agent that has infrequently been associated with cardiotoxicity. This review highlights the clinical features of this syndrome as described in reports from the medical literature. Clinical and laboratory evidence supporting proposed underlying mechanisms are reviewed.",

keywords = "5-Fluorouracil, Angina, Coronary spasm, Myocardial infarction, Thrombosis, Toxicity",

author = "Gradishar, {W. J.} and Vokes, {E. E.}",

year = "1990",

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AB - 5-Fluorouracil is a commonly administered chemotherapy agent that has infrequently been associated with cardiotoxicity. This review highlights the clinical features of this syndrome as described in reports from the medical literature. Clinical and laboratory evidence supporting proposed underlying mechanisms are reviewed.

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KW - Angina

KW - Coronary spasm

KW - Myocardial infarction

KW - Thrombosis

KW - Toxicity

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Review: 5-fluorouracil cardiotoxicity: A critical review

Abstract

Keywords

ASJC Scopus subject areas

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