Rewarding brain stimulation, hippocampal activity, and footstomping in the gerbil

Ronald C. Kramis; Aryeh Routtenberg

doi:10.1016/0031-9384(69)90004-3

Rewarding brain stimulation, hippocampal activity, and footstomping in the gerbil

Ronald C. Kramis^*, Aryeh Routtenberg

^*Corresponding author for this work

Psychology

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Eleven gerbils (Meriones) were tested for self-stimulation in posterior hypothalamic loci while hippocampal activity was monitored. Rewarding brain stimulation produced synchronization (theta) or regularization of hippocampal activity; no rebound of hippocampal desynchronization was observed immediately following termination of stimulation. Several seconds following termination of stimulation, however, "footstomping" behavior was observed. This activity was seen following, never during, rewarding brain stimulation. Hippocampal activity was most often desynchronized during this species-typical behavior pattern. Synchronization-desynchronization shifts in hippocampus previously thought to reflect reward-aversion were interpreted to reflect the participation of two mechanisms subserving, respectively, stimulus-related and motor-organizational processes.

Original language	English (US)
Pages (from-to)	7-8,IN1-IN2,9-11
Journal	Physiology and Behavior
Volume	4
Issue number	1
DOIs	https://doi.org/10.1016/0031-9384(69)90004-3
State	Published - Jan 1969

Keywords

Brain stimulation
Footstomping
Gerbil
Hippocampus
Hypothalamus
Medial forebrain bundle
Self-stimulation
Substantia nigra
Theta

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Behavioral Neuroscience

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10.1016/0031-9384(69)90004-3

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title = "Rewarding brain stimulation, hippocampal activity, and footstomping in the gerbil",

abstract = "Eleven gerbils (Meriones) were tested for self-stimulation in posterior hypothalamic loci while hippocampal activity was monitored. Rewarding brain stimulation produced synchronization (theta) or regularization of hippocampal activity; no rebound of hippocampal desynchronization was observed immediately following termination of stimulation. Several seconds following termination of stimulation, however, {"}footstomping{"} behavior was observed. This activity was seen following, never during, rewarding brain stimulation. Hippocampal activity was most often desynchronized during this species-typical behavior pattern. Synchronization-desynchronization shifts in hippocampus previously thought to reflect reward-aversion were interpreted to reflect the participation of two mechanisms subserving, respectively, stimulus-related and motor-organizational processes.",

keywords = "Brain stimulation, Footstomping, Gerbil, Hippocampus, Hypothalamus, Medial forebrain bundle, Self-stimulation, Substantia nigra, Theta",

author = "Kramis, {Ronald C.} and Aryeh Routtenberg",

note = "Funding Information: All gerbils were observed for preoperative elicitation of footstomping by aversive footshock. The gerbils were then implanted stereotaxically with two bipolar nichrome electrodes directed ipsilaterally; one was aimed at lateral hypothalamus and the other was aimed at dorsal hippocampus. A single 1The research was supported, in part, by United States Public Health Service Contract MH 11991 to A.R. was a N.D.E.A. Predoctoral Fellow.",

year = "1969",

month = jan,

doi = "10.1016/0031-9384(69)90004-3",

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AU - Kramis, Ronald C.

AU - Routtenberg, Aryeh

N1 - Funding Information: All gerbils were observed for preoperative elicitation of footstomping by aversive footshock. The gerbils were then implanted stereotaxically with two bipolar nichrome electrodes directed ipsilaterally; one was aimed at lateral hypothalamus and the other was aimed at dorsal hippocampus. A single 1The research was supported, in part, by United States Public Health Service Contract MH 11991 to A.R. was a N.D.E.A. Predoctoral Fellow.

PY - 1969/1

Y1 - 1969/1

N2 - Eleven gerbils (Meriones) were tested for self-stimulation in posterior hypothalamic loci while hippocampal activity was monitored. Rewarding brain stimulation produced synchronization (theta) or regularization of hippocampal activity; no rebound of hippocampal desynchronization was observed immediately following termination of stimulation. Several seconds following termination of stimulation, however, "footstomping" behavior was observed. This activity was seen following, never during, rewarding brain stimulation. Hippocampal activity was most often desynchronized during this species-typical behavior pattern. Synchronization-desynchronization shifts in hippocampus previously thought to reflect reward-aversion were interpreted to reflect the participation of two mechanisms subserving, respectively, stimulus-related and motor-organizational processes.

AB - Eleven gerbils (Meriones) were tested for self-stimulation in posterior hypothalamic loci while hippocampal activity was monitored. Rewarding brain stimulation produced synchronization (theta) or regularization of hippocampal activity; no rebound of hippocampal desynchronization was observed immediately following termination of stimulation. Several seconds following termination of stimulation, however, "footstomping" behavior was observed. This activity was seen following, never during, rewarding brain stimulation. Hippocampal activity was most often desynchronized during this species-typical behavior pattern. Synchronization-desynchronization shifts in hippocampus previously thought to reflect reward-aversion were interpreted to reflect the participation of two mechanisms subserving, respectively, stimulus-related and motor-organizational processes.

KW - Brain stimulation

KW - Footstomping

KW - Gerbil

KW - Hippocampus

KW - Hypothalamus

KW - Medial forebrain bundle

KW - Self-stimulation

KW - Substantia nigra

KW - Theta

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Rewarding brain stimulation, hippocampal activity, and footstomping in the gerbil

Abstract

Keywords

ASJC Scopus subject areas

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