Reye syndrome: Computed tomographic documentation of disordered intracerebral structure

Eric J. Russell, Robert D. Zimmerman, Norman E. Leeds*, Joseph French

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Four patients with well documented Reye syndrome were examined with noncontrast computed tomography. Acute findings are those of diffuse cerebral edema with low density in deep white matter, increased gray-white matter differentiation, and evidence of secondary ventricular compression. The diffuse nature of the changes is unlike the more focal pattern often seen in true viral encephalitis. Residual changes after severe diseases are those of nonspecific cerebral degeneration and are most pronounced in the frontal lobes. Atrophic ventricular dilatation was observed in two cases. Computed tomography findings correlate with all known pathologic studies and with the subsequent clinical courses in the patients examined.

Original languageEnglish (US)
Pages (from-to)217-220
Number of pages4
JournalJournal of Computer Assisted Tomography
Issue number2
StatePublished - Apr 1979


  • Brain
  • Brain
  • Computed tomography
  • Diseases
  • Edema
  • Reye syndrome
  • Viral associated disease

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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