In children, most cases of rhinosinusitis involve one of three bacteria, Streptococcus pneumoniae, Hemophilus influenzae, or Moraxella catarrhalis. However, multiple pathogens, including Staphylococcus aureus, Streptococcus pyogenes, anaerobes, gram-negative bacteria, fungi, and viruses may also be present. For treatment, amoxicillin alone is usually preferred. Where penicillin-resistant bacteria are highly prevalent, consider amoxicillin- clavulanate. Trimethoprimsulfamethoxazole, erythromycin-sulfisoxazole, cefuroxime axetil, cefpodoxime, and clarithromycin are suitable alternatives. Clinical improvement normally occurs within a few days. Depending on the rapidity of the clinical response, continue therapy for 2 to 3 weeks to avoid relapse. Complications involving the orbit or intracranial contents sometimes occur and are life-threatening.
|Original language||English (US)|
|Number of pages||10|
|Journal||Journal of Respiratory Diseases|
|State||Published - Dec 5 1998|
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine