RhoGTPases in stem cells

Hailei Yao, Xiaoyan Xie, Dongmei Wang, Xuetao Pei*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


RhoGTPases are small molecules that control a wide variety of signal transduction pathways. Their profound function in regulating the actin cytoskeleton is well recognized. Stem cells are unique in their ability to self-renew and produce progenitor cells that can differentiate into specialized cells. RhoGTPases influence stem cell morphology and cell migration as well as stem cell self-renewal, proliferation, transplantation, homing and differentiation. In this review, the multiple roles of the RhoGTPases in stem cells are discussed.

Original languageEnglish (US)
Pages (from-to)3025-3028
Number of pages4
JournalChinese Science Bulletin
Issue number22
StatePublished - Nov 2007
Externally publishedYes


  • Differentiation
  • Proliferation
  • RhoGTPases
  • Self-renewal
  • Stem cells

ASJC Scopus subject areas

  • General


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