Rigid region pairwise sequence alignment

Marko Zivanic*, Ovidiu Daescu, Anastasia Kurdia

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

We initiate a formal study of correlation between protein structural similarity and similarity of protein rigidity properties. In this paper we combine algorithmic techniques from protein sequence alignment and protein rigidity analysis and derive a new algorithm for protein sequence alignment, ultimately aiming at improving accuracy of protein homology detection and structure prediction, and also reducing the running time of currently known methods.

Original languageEnglish (US)
Title of host publication2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011
Pages319-326
Number of pages8
DOIs
StatePublished - 2011
Event2011 IEEE International Conference onBioinformatics and Biomedicine Workshops, BIBMW 2011 - Atlanta, GA, United States
Duration: Nov 12 2011Nov 15 2011

Publication series

Name2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011

Conference

Conference2011 IEEE International Conference onBioinformatics and Biomedicine Workshops, BIBMW 2011
Country/TerritoryUnited States
CityAtlanta, GA
Period11/12/1111/15/11

Keywords

  • protein rigidity and flexibility
  • Protein sequence alignment
  • protein structure prediction

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

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