Risk compensation in HIV PrEP adherence among Black men who have sex with men in HPTN 073 study

Darren L. Whitfield*, Geetha Beauchamp, Sheldon Fields, La Ron Nelson, Manya Magnus, Jagadīśa devaśrī Dācus, Jonathan Paul, Peter Anderson, Darrell Wheeler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


While HIV infections among men who have sex men (MSM) have started to decline in the United States, Black MSM continue to experience disproportionate rates of HIV infection. The purpose of this secondary analysis is to examine risk perception and its influence on PrEP adherence among Black MSM from HPTN 073. Risk perception was measured using the adapted Perceived Vulnerability to HIV Scale. The associations between risk perception and PrEP adherence were tested using generalized estimation equation model for time-variant repeated measures. Risk perception was not significantly associated with PrEP adherence. These findings suggest an there was no risk compensation among PrEP users, and inconsistency in perceived risk for HIV. Future studies should investigate the rationale for long term adherence to PrEP among Black MSM.

Original languageEnglish (US)
Pages (from-to)633-638
Number of pages6
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Issue number5
StatePublished - 2021


  • Black MSM
  • HIV pre-exposure prophylaxis
  • HIV prevention
  • behavioral compensation

ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health
  • Social Psychology


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