Risk factors for death during newborn and post-newborn hospitalizations among preterm infants

Nana Matoba*, Soyang Kwon, James W. Collins, Matthew M. Davis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Objectives: To examine risk factors for mortality among preterm infants during newborn and subsequent hospitalizations, and whether they differ by race/ethnicity. Study design: We conducted a cross-sectional analysis using the 2016 Kids Inpatient Database. Hospitalizations of preterm infants were categorized as “newborn” for birth admissions, and “post-newborn” for all others. Multivariate logistic regression was performed to calculate associations of mortality with sociodemographic factors. Results: Of 285915 hospitalizations, there were 7827 (2.7%) deaths. During newborn hospitalizations, adjusted OR (aOR) of death equaled 1.14 (95% CI 1.09–1.20) for males, 68.73 (61.91–76.30) for <29 weeks GA, and 0.81 (0.71–0.92) for transfer. Stratified by race/ethnicity, aOR was 0.69 (0.61–0.71) for Medicaid only among black infants. During post-newborn hospitalizations, death was associated with transfer (aOR 5.02, 3.31–7.61). Conclusions: Risk factors for death differ by hospitalization types and race/ethnicity. Analysis by hospitalization types may identify risk factors that inform public health interventions for reducing infant mortality.

Original languageEnglish (US)
Pages (from-to)1288-1293
Number of pages6
JournalJournal of Perinatology
Issue number10
StatePublished - Oct 2022

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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