Risk identification at the time of admission to coronary care unit in patients with suspected myocardial infarction

Mihai Gneorghiade*, Joseph Anderson, Howard Rosman, Jeffrey Lakier, Bernard Velardo, David Goldberg, Alan Friedman, Lonni Schultz, Barbara Tilley, Sidney Goldstein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

The in-hospital clinical course was evaluated in 2162 consecutive patients admitted with a diagnosis of suspected myocardial infarction. Of these, 1609 patients were considered to be in the high-risk group, based on the presence of 16 clinical criteria present at the time of admission. The remaining 553 patients were classified as low risk. The overall rate of complications in the coronary care unit was greater in the high-risk group, 64%, compared to 26% in the low-risk group (p < 0.001). Similarly life-threatening events (occurrence or recurrence of ventricular fibrillation, sustained ventricular tachycardia, complete heart block, asystole, or cardiogenic shock) were more common in the high risk-group compared to the low-risk group, 11% and 0.9%, respectively (p < 0.001). The high-risk group required significantly more interventions, such as electrical cardioversion, temporary pacing, pulmonary artery catheterization, and intraaortic balloon counterpulsation, compared to the low-risk group (20% vs 2%, respectively; p < 0.001). Myocardial infarction was confirmed in 892 patients in the high-risk group (55%) compared to 90 (16%) in the low-risk group (p < 0.001). The coronary care unit mortality rate was greater in the high-risk group compared to the low-risk group (8.2% vs 0.4%, respectively; p < 0.0002). It is concluded that based on readily available clinical criteria at the time of acmission, a subgroup of patients at low risk for developing life-threatening complications requiring coronary care unit interventions can be identified and admitted directly to an intermediate-care unit.

Original languageEnglish (US)
Pages (from-to)1212-1217
Number of pages6
JournalAmerican heart journal
Volume116
Issue number5 PART 1
DOIs
StatePublished - Nov 1988

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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