Risk of recurrence after a first unprovoked seizure

Anne T. Berg*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

116 Scopus citations

Abstract

The risk of recurrence after a first unprovoked seizure has been examined in numerous observational studies and two large, high-quality randomized trials. Overall, in untreated individuals, 40-50% can expect a recurrence within 2 years of the initial seizure. Treatment may reduce this risk by as much as half. Those at the greatest risk of recurrence have either an abnormal EEG or an identifiable neurological condition or symptoms consistent with one ("symptomatic"). Status epilepticus and a history of febrile seizures may be associated with an increased risk of recurrence in individuals with symptomatic seizures. The great majority of people (∼90%) who are seen for a first unprovoked seizure attain a one to two year remission within 4 or 5 years of the initial event.

Original languageEnglish (US)
Pages (from-to)13-18
Number of pages6
JournalEpilepsia
Volume49
Issue numberSUPPL. 1
DOIs
StatePublished - Jan 2008

Keywords

  • Epidemiology
  • Epilepsy
  • Recurrence risk
  • Seizure

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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