RNA interference: The fragile X syndrome connection

Richard W. Carthew*

*Corresponding author for this work

Research output: Contribution to journalReview article

27 Scopus citations

Abstract

Fragile X syndrome is caused by loss of expression of FMRP, a protein proposed to act as a regulator of mRNA translation which promotes synaptic maturation and function. Now FMRP has been found to associate with the RNP complex that mediates post-transcriptional silencing by RNAi.

Original languageEnglish (US)
Pages (from-to)R852-R854
JournalCurrent Biology
Volume12
Issue number24
DOIs
StatePublished - Dec 23 2002

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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