RNAi in Liver Diseases

Jiang Li*, Jianqin Lu, Yifei Zhang, Mohammed Ghazwani, Peng Zhang, Xiang Gao, Song Li

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter summarizes the roles of siRNAs and miRNAs in several common liver diseases including viral hepatitis, hepatocellular carcinoma, and liver fibrosis. Various delivery systems for siRNA and miRNA are also reviewed.

Original languageEnglish (US)
Title of host publicationAdvanced Delivery and Therapeutic Applications of RNAi
PublisherJohn Wiley and Sons
Pages327-366
Number of pages40
ISBN (Print)9781119976868
DOIs
StatePublished - Apr 26 2013
Externally publishedYes

Keywords

  • Cell-specific targeting
  • HBV
  • HCC
  • HCV
  • Lipid-based system
  • Liver fibrosis
  • Polymer-based system

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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